NIH: Findings in Mice Suggest Obesity Treatments - Diverse Health

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NIH: Findings in Mice Suggest Obesity Treatments

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by NIH

A team of scientists led by researchers from the National Institutes of Health has identified an enzyme that could help in the continuous battle against mid-life obesity and fitness loss. The discovery in mice could upend current notions about why people gain weight as they age, and could one day lead to more effective weight-loss medications.

“Our society attributes the weight gain and lack of exercise at mid-life (approximately 30-60 years) primarily to poor lifestyle choices and lack of will power, but this study shows that there is a genetic program driven by an overactive enzyme that promotes weight gain and loss of exercise capacity at mid-life,” said lead study author Jay H. Chung, Ph.D., M.D., head of the Laboratory of Obesity and Aging Research at the National Heart, Lung, and Blood Institute (NHLBI), part of NIH.

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